Proceedings from the 16th March 2007 meeting in Hertfordshire, UK



“The diversity of T cell subsets and functions makes it imperative that they can be identified, characterised, propagated, traced in vivo and their function elucidated effectively. This one day EuroSciCon meeting provided the ideal opportunity to hear both the commercial companies presenting new techniques and academics highlighting their latest findings in this area. Similarly, there were opportunities throughout the day for the audience to interact with the speakers and discuss their results in an informal setting.”  Chair- Dr Catherine Derry, Science Communicator


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Table of Contents



Identifying T Cell Subset Phenotype and Function: alpha/beta, gamma/delta, regulator, helper, NK& cytotoxic T cells

Magnetic Separation for T cell Subset Sorting & Identification

Tracking the interplay between antigen-specific naïve and regulatory T cells in vivo

Adoptive cell therapy with “customised” antigen-specific CD4+CD25+ Tregs

Functional characterization of CD4+CD25+ regulatory T cells − fundamental mechanisms and implications for the pathogenesis of autoimmune disease

A TRAP assay (Trogocytosis Analysis Protocol)  to detect, quantify, characterize and purify antigenspecific live lymphocytes by flow cytometry, via their capture of membrane fragments from antigen-presenting cells

The Maternal Immune Response in Pregnancy: an inflammatory view

  • Background
  • The two immune interfaces of pregnancy
  • Immune interactions at Interface 1
  • Immune interactions at Interface 2
  • Conclusions
  • References

Chronic Trichuris muris infection suppresses skin allergen responses and Langerhans cell migration

Instruction of effector CD4+ T lymphocytes by dendritic cells; the power of flow cytometry in immunological research

New differentiation pathway for double-negative regulatory T-cells that regulates the magnitude of immune responses


Inhibitory CpG ODN stimulated plasmacytoid dendritic cells induce CD4+CD25+Foxp3+ T cells

Induction of T regulatory cells by Cholera Toxin subunit B treated human monocyte-derived dendritic cells